What is the difference in the treatment of DKA versus the treatment of HHS?
The deficiency in insulin (either absolute or relative deficiency) is more severe in DKA compared with HHS. In HHS the residual insulin secretion and its systemic activity minimizes the development of ketoacidosis but it is not adequate to control hyperglycemia.
How can you tell the difference between DKA and HHS?
DKA is characterized by ketoacidosis and hyperglycemia, while HHS usually has more severe hyperglycemia but no ketoacidosis (table 1). Each represents an extreme in the spectrum of hyperglycemia.
How is HHNS treated?
Treatment. Treatment typically involves starting intravenous (IV) fluids (saline solution delivered through a needle into a vein) to rehydrate the body quickly. It also may require IV insulin to bring down blood sugar levels. If you are hospitalized due to HHNS, you may be kept overnight for observation.
What is the usual treatment procedure for correction of HHS?
Treatment of HHS Treatment is 0.9% (isotonic) saline solution at a rate of 15 to 20 mL/kg/hour, for the first few hours. After that, the corrected sodium should be calculated. If the corrected sodium is < 135 mEq/L (< 135 mmol/L), then isotonic saline should be continued at a rate of 250 to 500 mL/hour.
What are the most common factors for DKA and HHS What is the main difference in HHS?
Both DKA and HHS are characterized by hyperglycemia and absolute or relative insulinopenia. Clinically, they differ by the severity of dehydration, ketosis, and metabolic acidosis (17). DKA most often occurs in patients with T1D.
How is HHS and DKA treated?
The mainstays of treatment in both DKA and HHS are aggressive rehydration, insulin therapy, electrolyte replacement, and discovery and treatment of underlying precipitating events.
How is DKA and HHS treated?
What is the difference between honk and DKA?
The key distinction between DKA and HONK seems to be the fact that in HONk, there is still enough insulin to overcome the ketogenic effects of glucagon. Glucagon inhibits acetyl-CoA carboxylase, which normally converts acetyl-CoA into malonyl-CoA.
What is HHS healthcare?
The mission of the U.S. Department of Health and Human Services (HHS) is to enhance the health and well-being of all Americans, by providing for effective health and human services and by fostering sound, sustained advances in the sciences underlying medicine, public health, and social services.
What are the similarities and differences between HHS and DKA?
What is HHS protocol?
The principles of HHS treatment recommended in these guidelines are: Measure or calculate osmolality (2Na+ + glucose + urea) frequently to monitor the response to treatment. Use intravenous (IV) 0.9% sodium chloride solution as the principle fluid to restore circulating volume and reverse dehydration.
Does HHNS cause acidosis?
Acidosis in HHS is mainly a result of dehydration and compromised end-organ perfusion. Arterial blood gases should be monitored every 2 to 3 hours in HHS. The BUN and creatine levels are usually elevated reflecting prerenal azotemia.