Can females have hypogonadism?
Hypogonadism in females describes the inadequate function of the ovaries, with impaired production of germ cells (eggs) and sex hormones (oestrogen and progesterone). Primary hypogonadism refers to a condition of the ovaries (primary ovarian insufficiency/hypergonadotropic hypogonadism).
What is female hypogonadism?
Hypogonadism is a condition that causes decreased function of the gonads, which are the testes in males and the ovaries in females, and decreased production of sex hormones. You may be born with the condition or it can develop later in life from injury or infection.
What causes hypogonadotropic hypogonadism in females?
Causes. HH is caused by a lack of hormones that normally stimulate the ovaries or testes. These hormones include gonadotropin-releasing hormone (GnRH), follicle stimulating hormone (FSH) and luteinizing hormone (LH).
What are the effects of hypogonadism in female?
The complications of hypogonadism in untreated females include: menstrual irregularities. early menopause. infertility.
Can hypogonadism be genetic?
The most common genetic disorders that cause primary hypogonadism are Turner syndrome (in women) and Klinefelter syndrome (in men). If you already have other autoimmune disorders you may be at higher risk for autoimmune damage to the gonads.
Can a woman with hypogonadism get pregnant?
It’s possible for women with hypogonadism to become pregnant, but it may be difficult without the proper treatment. Hypogonadism that occurs in adult females can often cause infertility. If it’s untreated, these cases of hypogonadism may prevent a woman from being able to become pregnant.
Does hypogonadism cause infertility?
Introduction: Testosterone treatment for hypogonadism is detrimental for men in reproductive age as it impairs spermatogenesis, and therefore affects fertility. It is, therefore, not indicated in men with hypogonadism and infertility.
What is the main cause of hypogonadism?
How common is hypogonadotropic hypogonadism?
The incidence of congenital hypogonadotropic hypogonadism is approximately 1-10:100,000 live births, and approximately 2/3 and 1/3 of cases are caused by Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism, respectively.
How is female hypogonadotropic hypogonadism treated?
A female with hypogonadotropic hypogonadism is usually presented with two treatment options – combined gonadal hormone replacement or pulsatile gonadotropin releasing hormone. When a patient incurs a contraindication to hormonal therapy, the management of their endocrine disorder becomes much more challenging.
Is female hypogonadism curable?
Unless it’s caused by a treatable condition, hypogonadism is a chronic condition that may require lifelong treatment. Your sex hormone level may decrease if you stop treatment.
What happens if too much estrogen is produced?
High levels of estrogen may put you at higher risk of blood clots and stroke. Estrogen dominance may also increase your chances of thyroid dysfunction. This can cause symptoms such as fatigue and weight changes.
What is the incidence of congenital hypogonadotropic hypogonadism in the US?
The incidence of congenital hypogonadotropic hypogonadism is approximately 1-10:100,000 live births, and approximately 2/3 and 1/3 of cases are caused by Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism, respectively.
Female hypogonadism is a disorder or failure in the functioning of female reproductive organs, especially the ovaries. Sometimes there is a complete lack of or reduction in the release of female hormones due to a disorder in the functioning and coordination between the pituitary gland, the hypothalamus in the brain and the female sex organs.
What are the treatment options for hypogonadism?
Treatment of hypogonadism is directed at the underlying pathology where possible, helping the woman become fertile if desired, and preventing the long-term complications of hypoestrogenism (ie, osteoporosis, increased cardiovascular disease, and urogenital atrophy ).
How is hypogonadism diagnosed in primary care?
Prevalence, Diagnosis and Treatment of Hypogonadism in Primary Care Practice. We then follow them every 6 months with a rectal exam, a PSA and a testosterone assay. Liver function, hemoglobin and cholesterol levels are monitored every 6 months as well. If the PSA increases, we discontinue therapy and perform a biopsy.