Is G-CSF the same as Neupogen?
Neupogen, Granix and Zarxio are trade names for filgrastim. Granulocyte – colony stimulating factor (G-CSF) is another name for filgrastim. In some cases, health care professionals may use the trade name Neupogen, Granix or Zarxio when referring to the generic drug name filgrastim.
What is G-CSF Neupogen?
About: Filgrastim (Neupogen®, G-CSF) Filgrastim is a man-made version of G-CSF that stimulates white blood cell production, and in particular, neutrophil production. A neutrophil is a type of white blood cell that is responsible for fighting infection and is often decreased during cancer therapy.
What is G-CSF chemotherapy?
G-CSF is a type of growth factor. You might have G-CSF after chemotherapy to help your white blood cells recover after treatment. Or you might have it before and after a stem cell transplant. There are different types of G-CSF, including: lenograstim (Granocyte)
What is the difference between G-CSF and GM-CSF?
In summary, although G-CSF and GM-CSF are molecularly cloned myeloid growth factors, their biology and clinical effects differ. GM-CSF has a much wider activity spectrum in animals and humans. In persons with lung infection and/or ARDS, GM-CSF may be a safer drug than G-CSF.
How much does G-CSF cost?
About Filgrastim The lowest GoodRx price for the most common version of Neupogen is around $313.17, 24% off the average retail price of $414.74.
When should G-CSF be given?
G-CSF is usually started 24 hours or more after your chemotherapy finishes. You usually have it daily. Your doctor or pharmacist will tell you how many injections you need. Some types of G-CSF stay in the body for longer.
What is G-CSF for neutropenia?
Granulocyte colony stimulating factor (G-CSF) is a type of drug that doctors prescribe to manage neutropenia, which is the term for a lower-than-normal white blood cell count. People with neutropenia are at a higher risk of infection. Some cancers and certain types of chemotherapy can destroy white blood cells.
How quickly does G-CSF work?
This usually takes 5 to 7 days, although it can be longer. If you are having G-CSF before a stem cell transplant, you usually have your first dose 4 to 6 days before your stem cells are going to be collected.
What is a granulocyte?
(GRAN-yoo-loh-SITE) A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. Neutrophils, eosinophils, and basophils are granulocytes. A granulocyte is a type of white blood cell.
Is G-CSF injection painful?
The most relevant adverse event of G-CSF administration is bone pain. Approximately 20% of cancer patients experienced bone pain with the administration of prophylactic daily G-CSFs (lenograstim and filgrastim).
Is filgrastim a G-CSF?
What is this medicine? FILGRASTIM, G-CSF (fil GRA stim) is a granulocyte colony-stimulating factor that stimulates the growth of neutrophils, a type of white blood cell (WBC) important in the body’s fight against infection.
What is Neupogen ®?
NEUPOGEN ® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony stimulating factor (r- metHuG-CSF). NEUPOGEN is a 175 amino acid protein manufactured by recombinant DNA technology.
What is the role of G-CSF in neutropenia?
Further, G-CSF influences the function of mature neutrophils. These actions underpin its rapid uptake into clinical medicine as a drug that increases the production of neutrophils in patients with chemotherapy-induced neutropenia. Ongoing research has uncovered initially unsuspected polyfunctionality for G-CSF.
Is Neupogen the same as filgrastim?
1 NEUPOGEN ® (Filgrastim) DESCRIPTION Filgrastim is a human granulocyte colony stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN ® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony stimulating factor (r- metHuG-CSF).
Who should not take Neupogen ®?
Do not take NEUPOGEN ® if you have had a serious allergic reaction to human G-CSFs such as (filgrastim) or (pegfilgrastim) products. have a sickle cell disorder. have kidney problems.